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STL · 2025 transactions
Data through 2026-10-03
| Date | Player | Type | Detail |
|---|---|---|---|
| Dec 22 | Hunter Dobbins | Status Change | St. Louis Cardinals activated RHP Hunter Dobbins. |
| Dec 22 | Jared Shuster | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Jared Shuster to a minor league contract. |
| Dec 22 | Willson Contreras | Trade | Boston Red Sox traded RHP Hunter Dobbins, RHP Yhoiker Fajardo and RHP Blake Aita to St. Louis Cardinals for 1B Willson Contreras. |
| Dec 19 | Matt Koperniak | Outrighted | St. Louis Cardinals sent LF Matt Koperniak outright to Memphis Redbirds. |
| Dec 17 | Dustin May | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Dustin May. |
| Dec 17 | Matt Koperniak | Designated for Assignment | St. Louis Cardinals designated LF Matt Koperniak for assignment. |
| Dec 13 | Diego Conseción | Signed as Free Agent | St. Louis Cardinals signed free agent IF Diego Consecion to a minor league contract. |
| Dec 10 | Matt Pushard | Status Change | St. Louis Cardinals activated RHP Matt Pushard. |
| Dec 10 | Zane Mills | Rule 5 Draft Minors | Chicago Cubs purchased contract of RHP Zane Mills in the Rule 5 Draft, AAA Phase. |
| Dec 10 | Matt Lloyd | Rule 5 Draft Minors | Boston Red Sox purchased contract of 3B Matt Lloyd in the Rule 5 Draft, AAA Phase. |
| Dec 10 | Sean Harney | Rule 5 Draft Minors | Arizona Diamondbacks purchased contract of RHP Sean Harney in the Rule 5 Draft, AAA Phase. |
| Dec 10 | Ryan Murphy | Rule 5 Draft Minors | St. Louis Cardinals purchased contract of RHP Ryan Murphy in the Rule 5 Draft, AAA Phase. |
| Dec 10 | Cade Winquest | Rule 5 Selection | New York Yankees purchased contract of RHP Cade Winquest in the Rule 5 Draft. |
| Dec 10 | Matt Pushard | Rule 5 Selection | St. Louis Cardinals purchased contract of RHP Matt Pushard in the Rule 5 Draft. |
| Dec 5 | Zak Kent | Claimed Off Waivers | St. Louis Cardinals claimed RHP Zak Kent off waivers from Cleveland Guardians. |
| Nov 26 | Sem Robberse | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Sem Robberse to a minor league contract. |
| Nov 26 | Scott Blewett | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Scott Blewett to a minor league contract. |
| Nov 25 | Richard Fitts | Status Change | St. Louis Cardinals activated RHP Richard Fitts. |
| Nov 25 | Richard Fitts | Trade | St. Louis Cardinals traded RHP Sonny Gray and cash to Boston Red Sox for RHP Richard Fitts, LHP Brandon Clarke and Player To Be Named Later. |
| Nov 25 | Yohel Pozo | Signed as Free Agent | St. Louis Cardinals signed free agent C Yohel Pozo. |
| Nov 21 | Sem Robberse | Declared Free Agency | RHP Sem Robberse elected free agency. |
| Nov 21 | Yohel Pozo | Declared Free Agency | C Yohel Pozo elected free agency. |
| Nov 21 | John King | Declared Free Agency | LHP John King elected free agency. |
| Nov 21 | Jorge Alcala | Declared Free Agency | RHP Jorge Alcala elected free agency. |
| Nov 18 | Joshua Báez | Status Change | St. Louis Cardinals activated RF Joshua Baez. |
| Nov 18 | Brycen Mautz | Status Change | St. Louis Cardinals activated LHP Brycen Mautz. |
| Nov 18 | Cooper Hjerpe | Selected | St. Louis Cardinals selected the contract of LHP Cooper Hjerpe from Springfield Cardinals. |
| Nov 18 | Brycen Mautz | Selected | St. Louis Cardinals selected the contract of LHP Brycen Mautz from Springfield Cardinals. |
| Nov 18 | Leo Bernal | Selected | St. Louis Cardinals selected the contract of C Leonardo Bernal from Springfield Cardinals. |
| Nov 18 | Joshua Báez | Selected | St. Louis Cardinals selected the contract of RF Joshua Baez from Springfield Cardinals. |
| Nov 18 | Jorge Alcala | Designated for Assignment | St. Louis Cardinals designated RHP Jorge Alcala for assignment. |
| Nov 6 | Bryan Torres | Status Change | St. Louis Cardinals activated OF Bryan Torres. |
| Nov 6 | Bryan Torres | Selected | St. Louis Cardinals selected the contract of OF Bryan Torres from Memphis Redbirds. |
| Nov 6 | Zack Thompson | Outrighted | St. Louis Cardinals sent LHP Zack Thompson outright to Memphis Redbirds. |
| Nov 6 | Anthony Veneziano | Outrighted | St. Louis Cardinals sent LHP Anthony Veneziano outright to Memphis Redbirds. |
| Nov 6 | Zack Thompson | Status Change | St. Louis Cardinals activated LHP Zack Thompson from the 60-day injured list. |
| Nov 6 | Michael Siani | Claimed Off Waivers | Atlanta Braves claimed CF Michael Siani off waivers from St. Louis Cardinals. |
| Nov 6 | Roddery Muñoz | Claimed Off Waivers | Cincinnati Reds claimed RHP Roddery Muñoz off waivers from St. Louis Cardinals. |
| Nov 2 | Miles Mikolas | Declared Free Agency | RHP Miles Mikolas elected free agency. |
| Nov 1 | Andey Garrido | Signed as Free Agent | St. Louis Cardinals signed free agent OF Andey Garrido to a minor league contract. |
| Nov 1 | Saúl Figuereo | Signed as Free Agent | St. Louis Cardinals signed free agent OF Saul Figuereo to a minor league contract. |
| Oct 20 | Juan Santillán | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Juan Santillan to a minor league contract. |
| Sep 29 | Anthony Veneziano | Recalled | St. Louis Cardinals recalled LHP Anthony Veneziano from Memphis Redbirds. |
| Sep 29 | Michael Siani | Recalled | St. Louis Cardinals recalled CF Michael Siani from Memphis Redbirds. |
| Sep 29 | Sem Robberse | Recalled | St. Louis Cardinals recalled RHP Sem Robberse from Memphis Redbirds. |
| Sep 29 | Tekoah Roby | Recalled | St. Louis Cardinals recalled RHP Tekoah Roby from Memphis Redbirds. |
| Sep 29 | Nick Raquet | Recalled | St. Louis Cardinals recalled LHP Nick Raquet from Memphis Redbirds. |
| Sep 29 | César Prieto | Recalled | St. Louis Cardinals recalled 2B César Prieto from Memphis Redbirds. |
| Sep 29 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| Sep 29 | Matt Koperniak | Recalled | St. Louis Cardinals recalled LF Matt Koperniak from Memphis Redbirds. |
| Sep 29 | Tink Hence | Recalled | St. Louis Cardinals recalled RHP Tink Hence from Springfield Cardinals. |
| Sep 29 | Andre Granillo | Recalled | St. Louis Cardinals recalled RHP Andre Granillo from Memphis Redbirds. |
| Sep 29 | Willson Contreras | Status Change | St. Louis Cardinals activated 1B Willson Contreras from the 10-day injured list. |
| Sep 29 | Masyn Winn | Status Change | St. Louis Cardinals activated SS Masyn Winn from the 10-day injured list. |
| Sep 17 | Willson Contreras | Status Change | St. Louis Cardinals placed 1B Willson Contreras on the 10-day injured list retroactive to September 16, 2025. Right shoulder strain. |
| Sep 17 | José Fermín | Recalled | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| Sep 16 | Brendan Donovan | Number Change | 2B Brendan Donovan changed number to 33. |
| Sep 15 | Brendan Donovan | Number Change | 2B Brendan Donovan changed number to 21. |
| Sep 15 | Nolan Arenado | Status Change | St. Louis Cardinals activated 3B Nolan Arenado from the 10-day injured list. |
| Sep 15 | José Fermín | Optioned | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| Sep 13 | Masyn Winn | Status Change | St. Louis Cardinals placed SS Masyn Winn on the 10-day injured list. Torn meniscus in right knee. |
| Sep 13 | José Fermín | Recalled | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| Sep 12 | José Fermín | Optioned | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| Sep 12 | Nick Raquet | Optioned | St. Louis Cardinals optioned LHP Nick Raquet to Memphis Redbirds. |
| Sep 12 | John King | Status Change | St. Louis Cardinals activated LHP John King from the 15-day injured list. |
| Sep 12 | Brendan Donovan | Status Change | St. Louis Cardinals activated 2B Brendan Donovan from the 10-day injured list. |
| Sep 11 | Garrett Hampson | Released | St. Louis Cardinals released 2B Garrett Hampson. |
| Sep 10 | John King | Assigned | St. Louis Cardinals sent LHP John King on a rehab assignment to Springfield Cardinals. |
| Sep 10 | John King | Assigned | St. Louis Cardinals sent LHP John King on a rehab assignment to Springfield Cardinals. |
| Sep 10 | Nolan Arenado | Assigned | St. Louis Cardinals sent 3B Nolan Arenado on a rehab assignment to Springfield Cardinals. |
| Sep 9 | Brendan Donovan | Assigned | St. Louis Cardinals sent 2B Brendan Donovan on a rehab assignment to Springfield Cardinals. |
| Sep 9 | Willson Contreras | Status Change | St. Louis Cardinals activated 1B Willson Contreras. |
| Sep 9 | Brendan Donovan | Assigned | St. Louis Cardinals sent 2B Brendan Donovan on a rehab assignment to Springfield Cardinals. |
| Sep 8 | Nick Raquet | Selected | St. Louis Cardinals selected the contract of LHP Nick Raquet from Memphis Redbirds. |
| Sep 8 | Alec Burleson | Status Change | St. Louis Cardinals activated 1B Alec Burleson from the 10-day injured list. |
| Sep 8 | Andre Granillo | Optioned | St. Louis Cardinals optioned RHP Andre Granillo to Memphis Redbirds. |
| Sep 8 | Garrett Hampson | Designated for Assignment | St. Louis Cardinals designated 2B Garrett Hampson for assignment. |
| Sep 5 | Yohel Pozo | Status Change | St. Louis Cardinals activated C Yohel Pozo from the 7-day injured list. |
| Sep 5 | César Prieto | Optioned | St. Louis Cardinals optioned 2B César Prieto to Memphis Redbirds. |
| Sep 5 | Willson Contreras | Suspension | 1B Willson Contreras suspended. |
| Sep 1 | Chris Roycroft | Recalled | St. Louis Cardinals recalled RHP Chris Roycroft from Memphis Redbirds. |
| Sep 1 | Victor Scott II | Status Change | St. Louis Cardinals activated CF Victor Scott II from the 10-day injured list. |
| Aug 29 | Victor Scott II | Assigned | St. Louis Cardinals sent CF Victor Scott II on a rehab assignment to Springfield Cardinals. |
| Aug 29 | Victor Scott II | Assigned | St. Louis Cardinals sent CF Victor Scott II on a rehab assignment to Springfield Cardinals. |
| Aug 29 | Jimmy Crooks | Selected | St. Louis Cardinals selected the contract of C Jimmy Crooks from Memphis Redbirds. |
| Aug 29 | César Prieto | Selected | St. Louis Cardinals selected the contract of 2B César Prieto from Memphis Redbirds. |
| Aug 29 | Alec Burleson | Status Change | St. Louis Cardinals placed 1B Alec Burleson on the 10-day injured list. Right wrist inflammation. |
| Aug 29 | Yohel Pozo | Status Change | St. Louis Cardinals placed C Yohel Pozo on the 7-day injured list. |
| Aug 27 | John King | Status Change | St. Louis Cardinals placed LHP John King on the 15-day injured list retroactive to August 26, 2025. Mid-back strain. |
| Aug 27 | Andre Granillo | Recalled | St. Louis Cardinals recalled RHP Andre Granillo from Memphis Redbirds. |
| Aug 25 | Andre Granillo | Optioned | St. Louis Cardinals optioned RHP Andre Granillo to Memphis Redbirds. |
| Aug 25 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Aug 24 | Anthony Veneziano | Optioned | St. Louis Cardinals optioned LHP Anthony Veneziano to Memphis Redbirds. |
| Aug 24 | John King | Status Change | St. Louis Cardinals activated LHP John King from the 15-day injured list. |
| Aug 18 | Brendan Donovan | Status Change | St. Louis Cardinals placed 2B Brendan Donovan on the 10-day injured list retroactive to August 15, 2025. Left groin strain. |
| Aug 18 | José Fermín | Recalled | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| Aug 17 | Nathan Church | Selected | St. Louis Cardinals selected the contract of LF Nathan Church from Memphis Redbirds. |
| Aug 17 | Anthony Veneziano | Recalled | St. Louis Cardinals recalled LHP Anthony Veneziano from Memphis Redbirds. |
| Aug 17 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| Aug 17 | Victor Scott II | Status Change | St. Louis Cardinals placed CF Victor Scott II on the 10-day injured list. Left ankle sprain. |
| Aug 16 | John King | Assigned | St. Louis Cardinals sent LHP John King on a rehab assignment to Memphis Redbirds. |
| Aug 16 | John King | Assigned | St. Louis Cardinals sent LHP John King on a rehab assignment to Memphis Redbirds. |
| Aug 12 | Andrew Sojka | Signed as Free Agent | St. Louis Cardinals signed free agent OF Andrew Sojka to a minor league contract. |
| Aug 10 | Jorge Alcala | Status Change | St. Louis Cardinals activated RHP Jorge Alcala. |
| Aug 10 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Aug 7 | Jorge Alcala | Claimed Off Waivers | St. Louis Cardinals claimed RHP Jorge Alcala off waivers from Boston Red Sox. |
| Aug 4 | Anthony Veneziano | Optioned | St. Louis Cardinals optioned LHP Anthony Veneziano to Memphis Redbirds. |
| Aug 4 | Anthony Veneziano | Claimed Off Waivers | St. Louis Cardinals claimed LHP Anthony Veneziano off waivers from Miami Marlins. |
| Aug 4 | Luken Baker | Claimed Off Waivers | Los Angeles Dodgers claimed 1B Luken Baker off waivers from St. Louis Cardinals. |
| Aug 2 | Lars Nootbaar | Status Change | St. Louis Cardinals placed LF Lars Nootbaar on the 60-day injured list. Bilateral Haglund's Deformity excision. |
| Aug 2 | Lars Nootbaar | Status Change | St. Louis Cardinals activated LF Lars Nootbaar from the 10-day injured list. |
| Aug 2 | José Fermín | Optioned | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| Aug 1 | Ryan Fernandez | Recalled | St. Louis Cardinals recalled RHP Ryan Fernandez from Memphis Redbirds. |
| Aug 1 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| Aug 1 | Andre Granillo | Recalled | St. Louis Cardinals recalled RHP Andre Granillo from Memphis Redbirds. |
| Aug 1 | Nolan Arenado | Status Change | St. Louis Cardinals placed 3B Nolan Arenado on the 10-day injured list. Right shoulder strain. |
| Jul 31 | Gerson Moreno | Assigned | RHP Gerson Moreno assigned to St. Louis Cardinals. |
| Jul 31 | Gerson Moreno | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Gerson Moreno to a minor league contract. |
| Jul 31 | Mason Molina | Trade | St. Louis Cardinals traded RHP Phil Maton to Texas Rangers for LHP Mason Molina, RHP Skylar Hales and Future Considerations. International Bonus Pool Money. |
| Jul 31 | Blaze Jordan | Trade | St. Louis Cardinals traded LHP Steven Matz to Boston Red Sox for 1B Blaze Jordan. |
| Jul 30 | Jesús Báez | Trade | St. Louis Cardinals traded RHP Ryan Helsley to New York Mets for SS Jesus Baez, RHP Frank Elissalt and RHP Nate Dohm. |
| Jul 30 | John King | Status Change | St. Louis Cardinals placed LHP John King on the 15-day injured list. Left oblique strain. |
| Jul 30 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Jul 30 | Lars Nootbaar | Assigned | St. Louis Cardinals sent LF Lars Nootbaar on a rehab assignment to Springfield Cardinals. |
| Jul 29 | Nolan Gorman | Assigned | St. Louis Cardinals sent 2B Nolan Gorman on a rehab assignment to Springfield Cardinals. |
| Jul 28 | Andre Granillo | Optioned | St. Louis Cardinals optioned RHP Andre Granillo to Memphis Redbirds. |
| Jul 28 | Matt Svanson | Recalled | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| Jul 27 | — | Trade | St. Louis Cardinals traded RHP Erick Fedde and cash to Atlanta Braves for Future Considerations. |
| Jul 23 | Lucas Takahashi | Signed as Free Agent | St. Louis Cardinals signed free agent CF Lucas Takahashi to a minor league contract. |
| Jul 23 | Erick Fedde | Designated for Assignment | St. Louis Cardinals designated RHP Erick Fedde for assignment. |
| Jul 23 | Andre Granillo | Recalled | St. Louis Cardinals recalled RHP Andre Granillo from Memphis Redbirds. |
| Jul 22 | Jalin Flores | Signed | St. Louis Cardinals signed SS Jalin Flores. |
| Jul 21 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Jul 21 | Michael McGreevy | Recalled | St. Louis Cardinals recalled RHP Michael McGreevy from Memphis Redbirds. |
| Jul 19 | Jack Gurevitch | Signed | St. Louis Cardinals signed 1B Jack Gurevitch. |
| Jul 19 | Ethan Young | Signed | St. Louis Cardinals signed RHP Ethan Young. |
| Jul 19 | Ryan Weingartner | Signed | St. Louis Cardinals signed SS Ryan Weingartner. |
| Jul 19 | Anthony Watts | Signed | St. Louis Cardinals signed RHP Anthony Watts. |
| Jul 19 | Jake Shelagowski | Signed | St. Louis Cardinals signed RHP Jake Shelagowski. |
| Jul 19 | Bobby Olsen | Signed | St. Louis Cardinals signed RHP Bobby Olsen. |
| Jul 19 | Cameron Nickens | Signed | St. Louis Cardinals signed OF Cameron Nickens. |
| Jul 19 | Matthew Miura | Signed | St. Louis Cardinals signed OF Matthew Miura. |
| Jul 19 | Ryan Mitchell | Signed | St. Louis Cardinals signed OF Ryan Mitchell. |
| Jul 19 | Chase Heath | Signed | St. Louis Cardinals signed C Chase Heath. |
| Jul 19 | Trevor Haskins | Signed | St. Louis Cardinals signed SS Trevor Haskins. |
| Jul 19 | Payton Graham | Signed | St. Louis Cardinals signed RHP Payton Graham. |
| Jul 19 | Tanner Franklin | Signed | St. Louis Cardinals signed RHP Tanner Franklin. |
| Jul 19 | Kaden Echeman | Signed | St. Louis Cardinals signed RHP Kaden Echeman. |
| Jul 19 | Dylan Driessen | Signed | St. Louis Cardinals signed RHP Dylan Driessen. |
| Jul 19 | Michael Dattalo | Signed | St. Louis Cardinals signed 3B Michael Dattalo. |
| Jul 19 | Cade Crossland | Signed | St. Louis Cardinals signed LHP Cade Crossland. |
| Jul 19 | Alex Breckheimer | Signed | St. Louis Cardinals signed RHP Alex Breckheimer. |
| Jul 19 | Alex Birge | Signed | St. Louis Cardinals signed C Alex Birge. |
| Jul 19 | Liam Best | Signed | St. Louis Cardinals signed RHP Liam Best. |
| Jul 19 | Nolan Gorman | Status Change | St. Louis Cardinals placed 2B Nolan Gorman on the 10-day injured list retroactive to July 13, 2025. Lower back pain. |
| Jul 19 | Thomas Saggese | Recalled | St. Louis Cardinals recalled 2B Thomas Saggese from Memphis Redbirds. |
| Jul 18 | Aaron Wilkerson | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Aaron Wilkerson to a minor league contract. |
| Jul 18 | Jordan Walker | Status Change | St. Louis Cardinals activated RF Jordan Walker from the 10-day injured list. |
| Jul 17 | Thomas Saggese | Optioned | St. Louis Cardinals optioned 2B Thomas Saggese to Memphis Redbirds. |
| Jul 16 | Liam Doyle | Signed | St. Louis Cardinals signed LHP Liam Doyle. |
| Jul 14 | Ty Van Dyke | Signed | St. Louis Cardinals signed RHP Ty Van Dyke. |
| Jul 13 | Lars Nootbaar | Status Change | St. Louis Cardinals placed LF Lars Nootbaar on the 10-day injured list. Left costochondral sprain. |
| Jul 13 | Iván Herrera | Status Change | St. Louis Cardinals activated C Iván Herrera from the 10-day injured list. |
| Jul 12 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Jul 12 | Matt Svanson | Optioned | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| Jul 10 | Iván Herrera | Assigned | St. Louis Cardinals sent C Iván Herrera on a rehab assignment to Memphis Redbirds. |
| Jul 10 | Iván Herrera | Assigned | St. Louis Cardinals sent C Iván Herrera on a rehab assignment to Memphis Redbirds. |
| Jul 2 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Springfield Cardinals. |
| Jul 2 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Springfield Cardinals. |
| Jul 2 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Springfield Cardinals. |
| Jun 28 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Memphis Redbirds. |
| Jun 28 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Memphis Redbirds. |
| Jun 27 | José Barrero | Outrighted | St. Louis Cardinals sent SS Jose Barrero outright to Memphis Redbirds. |
| Jun 25 | José Fermín | Recalled | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| Jun 25 | Matt Svanson | Recalled | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| Jun 25 | Michael McGreevy | Optioned | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| Jun 24 | Zeke Wood | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Zeke Wood to a minor league contract. |
| Jun 24 | Domenic Picone | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Domenic Picone to a minor league contract. |
| Jun 24 | Garrett Hampson | Claimed Off Waivers | St. Louis Cardinals claimed 2B Garrett Hampson off waivers from Cincinnati Reds. |
| Jun 24 | José Barrero | Designated for Assignment | St. Louis Cardinals designated SS Jose Barrero for assignment. |
| Jun 24 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| Jun 24 | Michael McGreevy | Recalled | St. Louis Cardinals recalled RHP Michael McGreevy from Memphis Redbirds. |
| Jun 23 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Jun 23 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| Jun 22 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Jun 22 | Andre Granillo | Optioned | St. Louis Cardinals optioned RHP Andre Granillo to Memphis Redbirds. |
| Jun 20 | Iván Herrera | Status Change | St. Louis Cardinals placed C Iván Herrera on the 10-day injured list. Left hamstring strain. |
| Jun 20 | Thomas Saggese | Recalled | St. Louis Cardinals recalled SS Thomas Saggese from Memphis Redbirds. |
| Jun 20 | Michael McGreevy | Optioned | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| Jun 19 | Tyler Matzek | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Tyler Matzek to a minor league contract. |
| Jun 19 | Michael McGreevy | Recalled | St. Louis Cardinals recalled RHP Michael McGreevy from Memphis Redbirds. |
| Jun 14 | Ryan Vilade | Claimed Off Waivers | Cincinnati Reds claimed RF Ryan Vilade off waivers from St. Louis Cardinals. |
| Jun 14 | Jordan Walker | Status Change | St. Louis Cardinals activated RF Jordan Walker from the 10-day injured list. |
| Jun 14 | Michael Siani | Optioned | St. Louis Cardinals optioned CF Michael Siani to Memphis Redbirds. |
| Jun 13 | Héctor Cabrera | Signed as Free Agent | St. Louis Cardinals signed free agent C Hector Cabrera to a minor league contract. |
| Jun 13 | Ryan Vilade | Status Change | RF Ryan Vilade roster status changed by St. Louis Cardinals. |
| Jun 12 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Memphis Redbirds. |
| Jun 12 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Memphis Redbirds. |
| Jun 12 | Ryan Vilade | Designated for Assignment | St. Louis Cardinals designated RF Ryan Vilade for assignment. |
| Jun 12 | Jordan Walker | Assigned | St. Louis Cardinals sent RF Jordan Walker on a rehab assignment to Memphis Redbirds. |
| Jun 12 | Michael Siani | Recalled | St. Louis Cardinals recalled CF Michael Siani from Memphis Redbirds. |
| Jun 12 | Andre Granillo | Selected | St. Louis Cardinals selected the contract of RHP Andre Granillo from Memphis Redbirds. |
| Jun 12 | Chris Roycroft | Optioned | St. Louis Cardinals optioned RHP Chris Roycroft to Memphis Redbirds. |
| Jun 9 | Chris Roycroft | Recalled | St. Louis Cardinals recalled RHP Chris Roycroft from Memphis Redbirds. |
| Jun 9 | Riley O'Brien | Recalled | St. Louis Cardinals recalled RHP Riley O'Brien from Memphis Redbirds. |
| Jun 9 | Matt Svanson | Optioned | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| Jun 9 | Michael McGreevy | Optioned | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| Jun 8 | Zach Plesac | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Zach Plesac to a minor league contract. |
| Jun 8 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| Jun 8 | Michael McGreevy | Recalled | St. Louis Cardinals recalled RHP Michael McGreevy from Memphis Redbirds. |
| Jun 6 | Riley O'Brien | Optioned | St. Louis Cardinals optioned RHP Riley O'Brien to Memphis Redbirds. |
| Jun 5 | Riley O'Brien | Recalled | St. Louis Cardinals recalled RHP Riley O'Brien from Memphis Redbirds. |
| Jun 4 | Briam Reyes | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Briam Reyes to a minor league contract. |
| Jun 3 | Tyler Matzek | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Tyler Matzek to a minor league contract. |
| Jun 2 | Domingo Mejía | Signed as Free Agent | St. Louis Cardinals signed free agent Domingo Mejia to a minor league contract. |
| May 31 | Ryan Vilade | Selected | St. Louis Cardinals selected the contract of LF Ryan Vilade from Memphis Redbirds. |
| May 31 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| May 31 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| May 31 | Jordan Walker | Status Change | St. Louis Cardinals placed RF Jordan Walker on the 10-day injured list retroactive to May 29, 2025. Left wrist inflammation. |
| May 23 | Matt Svanson | Recalled | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| May 23 | Chris Roycroft | Optioned | St. Louis Cardinals optioned RHP Chris Roycroft to Memphis Redbirds. |
| May 22 | Ricardo Fernández | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Ricardo Fernandez to a minor league contract. |
| May 15 | Matt Svanson | Optioned | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| May 14 | Michael Helman | Claimed Off Waivers | Pittsburgh Pirates claimed CF Michael Helman off waivers from St. Louis Cardinals. |
| May 14 | Matt Svanson | Recalled | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| May 9 | Iván Herrera | Status Change | St. Louis Cardinals activated C Iván Herrera from the 10-day injured list. |
| May 8 | Luken Baker | Optioned | St. Louis Cardinals optioned 1B Luken Baker to Memphis Redbirds. |
| May 7 | Kriscol Peralta | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Kriscol Peralta to a minor league contract. |
| May 5 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| May 5 | Michael McGreevy | Optioned | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| May 5 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| May 5 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| May 4 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| May 3 | Michael McGreevy | Recalled | St. Louis Cardinals recalled RHP Michael McGreevy from Memphis Redbirds. |
| May 3 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| May 2 | Roddery Muñoz | Status Change | St. Louis Cardinals activated RHP Roddery Muñoz. |
| May 2 | Matt Svanson | Optioned | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| May 2 | Riley O'Brien | Optioned | St. Louis Cardinals optioned RHP Riley O'Brien to Memphis Redbirds. |
| May 2 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| May 2 | Chris Roycroft | Recalled | St. Louis Cardinals recalled RHP Chris Roycroft from Memphis Redbirds. |
| May 1 | Iván Herrera | Assigned | St. Louis Cardinals sent C Iván Herrera on a rehab assignment to Memphis Redbirds. |
| May 1 | — | Trade | St. Louis Cardinals traded RHP Ryan Loutos to Los Angeles Dodgers for cash. |
| May 1 | Iván Herrera | Assigned | St. Louis Cardinals sent C Iván Herrera on a rehab assignment to Memphis Redbirds. |
| May 1 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Apr 30 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Apr 28 | Thomas Saggese | Optioned | St. Louis Cardinals optioned SS Thomas Saggese to Memphis Redbirds. |
| Apr 28 | José Barrero | Selected | St. Louis Cardinals selected the contract of SS Jose Barrero from Memphis Redbirds. |
| Apr 28 | Ryan Loutos | Designated for Assignment | St. Louis Cardinals designated RHP Ryan Loutos for assignment. |
| Apr 26 | Efrén Álvarez | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Efren Alvarez to a minor league contract. |
| Apr 25 | Ryan Fernandez | Optioned | St. Louis Cardinals optioned RHP Ryan Fernandez to Memphis Redbirds. |
| Apr 25 | Riley O'Brien | Recalled | St. Louis Cardinals recalled RHP Riley O'Brien from Memphis Redbirds. |
| Apr 22 | Masyn Winn | Status Change | St. Louis Cardinals activated SS Masyn Winn from the 10-day injured list. |
| Apr 22 | Michael Siani | Optioned | St. Louis Cardinals optioned CF Michael Siani to Memphis Redbirds. |
| Apr 18 | Conor Steinbaugh | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Conor Steinbaugh to a minor league contract. |
| Apr 18 | Masyn Winn | Assigned | St. Louis Cardinals sent SS Masyn Winn on a rehab assignment to Memphis Redbirds. |
| Apr 16 | Luken Baker | Status Change | St. Louis Cardinals activated 1B Luken Baker. |
| Apr 16 | Luken Baker | Status Change | St. Louis Cardinals activated 1B Luken Baker. |
| Apr 16 | Roddery Muñoz | Status Change | St. Louis Cardinals activated RHP Roddery Muñoz. |
| Apr 16 | Andy Yerzy | Signed as Free Agent | St. Louis Cardinals signed free agent C Andy Yerzy to a minor league contract. |
| Apr 16 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| Apr 16 | Matt Svanson | Recalled | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| Apr 16 | Lars Nootbaar | Number Change | RF Lars Nootbaar changed number to 21. |
| Apr 16 | Ryan Helsley | Number Change | RHP Ryan Helsley changed number to 56. |
| Apr 16 | Miles Mikolas | Number Change | RHP Miles Mikolas changed number to 39. |
| Apr 16 | Brendan Donovan | Number Change | IF Brendan Donovan changed number to 33. |
| Apr 16 | Steven Matz | Number Change | LHP Steven Matz changed number to 32. |
| Apr 16 | Nolan Arenado | Number Change | 3B Nolan Arenado changed number to 28. |
| Apr 16 | Matthew Liberatore | Number Change | LHP Matthew Liberatore changed number to 52. |
| Apr 16 | Andre Pallante | Number Change | RHP Andre Pallante changed number to 53. |
| Apr 16 | Nolan Gorman | Number Change | 2B Nolan Gorman changed number to 16. |
| Apr 16 | Willson Contreras | Number Change | 1B Willson Contreras changed number to 40. |
| Apr 16 | JoJo Romero | Number Change | LHP JoJo Romero changed number to 59. |
| Apr 16 | Sonny Gray | Number Change | RHP Sonny Gray changed number to 54. |
| Apr 16 | Alec Burleson | Number Change | 1B Alec Burleson changed number to 41. |
| Apr 16 | Ryan Fernandez | Number Change | RHP Ryan Fernandez changed number to 64. |
| Apr 16 | Michael Siani | Number Change | CF Michael Siani changed number to 22. |
| Apr 16 | Luken Baker | Number Change | 1B Luken Baker changed number to 26. |
| Apr 16 | John King | Number Change | LHP John King changed number to 47. |
| Apr 16 | Jordan Walker | Number Change | RF Jordan Walker changed number to 18. |
| Apr 16 | Pedro Pagés | Number Change | C Pedro Pagés changed number to 43. |
| Apr 16 | Roddery Muñoz | Number Change | RHP Roddery Muñoz changed number to 35. |
| Apr 16 | Kyle Leahy | Number Change | RHP Kyle Leahy changed number to 62. |
| Apr 16 | Victor Scott II | Number Change | CF Victor Scott II changed number to 11. |
| Apr 16 | Yohel Pozo | Number Change | C Yohel Pozo changed number to 63. |
| Apr 16 | Thomas Saggese | Number Change | 2B Thomas Saggese changed number to 25. |
| Apr 16 | Erick Fedde | Number Change | RHP Erick Fedde changed number to 12. |
| Apr 16 | Phil Maton | Number Change | RHP Phil Maton changed number to 88. |
| Apr 15 | Roddery Muñoz | Status Change | St. Louis Cardinals reassigned RHP Roddery Muñoz to the minor leagues. |
| Apr 15 | Ricardo Velez | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Ricardo Velez to a minor league contract. |
| Apr 15 | Miles Mikolas | Number Change | RHP Miles Mikolas changed number to 42. |
| Apr 15 | Steven Matz | Number Change | LHP Steven Matz changed number to 42. |
| Apr 15 | Nolan Arenado | Number Change | 3B Nolan Arenado changed number to 42. |
| Apr 15 | Brendan Donovan | Number Change | IF Brendan Donovan changed number to 42. |
| Apr 15 | Lars Nootbaar | Number Change | RF Lars Nootbaar changed number to 42. |
| Apr 15 | Ryan Helsley | Number Change | RHP Ryan Helsley changed number to 42. |
| Apr 15 | Andre Pallante | Number Change | RHP Andre Pallante changed number to 42. |
| Apr 15 | JoJo Romero | Number Change | LHP JoJo Romero changed number to 42. |
| Apr 15 | Nolan Gorman | Number Change | 2B Nolan Gorman changed number to 42. |
| Apr 15 | Matthew Liberatore | Number Change | LHP Matthew Liberatore changed number to 42. |
| Apr 15 | Willson Contreras | Number Change | 1B Willson Contreras changed number to 42. |
| Apr 15 | Alec Burleson | Number Change | 1B Alec Burleson changed number to 42. |
| Apr 15 | John King | Number Change | LHP John King changed number to 42. |
| Apr 15 | Sonny Gray | Number Change | RHP Sonny Gray changed number to 42. |
| Apr 15 | Jordan Walker | Number Change | RF Jordan Walker changed number to 42. |
| Apr 15 | Michael Siani | Number Change | CF Michael Siani changed number to 42. |
| Apr 15 | Pedro Pagés | Number Change | C Pedro Pagés changed number to 42. |
| Apr 15 | Ryan Fernandez | Number Change | RHP Ryan Fernandez changed number to 42. |
| Apr 15 | Luken Baker | Number Change | 1B Luken Baker changed number to 42. |
| Apr 15 | Roddery Muñoz | Number Change | RHP Roddery Muñoz changed number to 42. |
| Apr 15 | Thomas Saggese | Number Change | 2B Thomas Saggese changed number to 42. |
| Apr 15 | Erick Fedde | Number Change | RHP Erick Fedde changed number to 42. |
| Apr 15 | Victor Scott II | Number Change | CF Victor Scott II changed number to 42. |
| Apr 15 | Kyle Leahy | Number Change | RHP Kyle Leahy changed number to 42. |
| Apr 15 | Phil Maton | Number Change | RHP Phil Maton changed number to 42. |
| Apr 15 | Yohel Pozo | Number Change | C Yohel Pozo changed number to 42. |
| Apr 12 | Masyn Winn | Status Change | St. Louis Cardinals placed SS Masyn Winn on the 10-day injured list. Lower back spasms. |
| Apr 12 | Nolan Gorman | Status Change | St. Louis Cardinals activated 2B Nolan Gorman from the 10-day injured list. |
| Apr 11 | Roddery Muñoz | Recalled | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| Apr 10 | Chris Roycroft | Optioned | St. Louis Cardinals optioned RHP Chris Roycroft to Memphis Redbirds. |
| Apr 7 | Yohel Pozo | Selected | St. Louis Cardinals selected the contract of C Yohel Pozo from Memphis Redbirds. |
| Apr 7 | Zack Thompson | Status Change | St. Louis Cardinals transferred LHP Zack Thompson from the 15-day injured list to the 60-day injured list. Left shoulder strain. |
| Apr 7 | Iván Herrera | Status Change | St. Louis Cardinals placed C Iván Herrera on the 10-day injured list. Left knee inflammation. |
| Apr 7 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Apr 6 | Gordon Graceffo | Recalled | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| Apr 4 | Nolan Gorman | Status Change | St. Louis Cardinals placed 2B Nolan Gorman on the 10-day injured list retroactive to April 2, 2025. Right hamstring strain. |
| Apr 4 | Thomas Saggese | Recalled | St. Louis Cardinals recalled 2B Thomas Saggese from Memphis Redbirds. |
| Mar 31 | Aaron Holiday | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Aaron Holiday to a minor league contract. |
| Mar 25 | Sean Harney | Status Change | RHP Sean Harney roster status changed by St. Louis Cardinals. |
| Mar 25 | Sean Harney | Trade | New York Mets traded RHP Sean Harney to St. Louis Cardinals. |
| Mar 24 | Kleininger Teran | Assigned | 3B Kleininger Teran assigned to St. Louis Cardinals. |
| Mar 24 | Zack Thompson | Status Change | St. Louis Cardinals placed LHP Zack Thompson on the 15-day injured list. Left shoulder strain. |
| Mar 23 | Michael McGreevy | Optioned | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| Mar 23 | José Fermín | Optioned | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| Mar 23 | José Davila | Assigned | RHP Jose Davila assigned to St. Louis Cardinals. |
| Mar 23 | Cade McGee | Assigned | 3B Cade McGee assigned to St. Louis Cardinals. |
| Mar 22 | Bryce Madron | Assigned | OF Bryce Madron assigned to St. Louis Cardinals. |
| Mar 22 | Trey Paige | Assigned | 3B Trey Paige assigned to St. Louis Cardinals. |
| Mar 19 | Chance Sisco | Released | St. Louis Cardinals released C Chance Sisco. |
| Mar 19 | Christian Martin | Assigned | 2B Christian Martin assigned to St. Louis Cardinals. |
| Mar 18 | Ryan Campos | Assigned | C Ryan Campos assigned to St. Louis Cardinals. |
| Mar 17 | Ramon Mendoza | Assigned | 2B Ramon Mendoza assigned to St. Louis Cardinals. |
| Mar 16 | Matt Koperniak | Optioned | St. Louis Cardinals optioned LF Matt Koperniak to Memphis Redbirds. |
| Mar 16 | Thomas Saggese | Optioned | St. Louis Cardinals optioned 2B Thomas Saggese to Memphis Redbirds. |
| Mar 16 | Michael Helman | Optioned | St. Louis Cardinals optioned CF Michael Helman to Memphis Redbirds. |
| Mar 15 | Riley O'Brien | Optioned | St. Louis Cardinals optioned RHP Riley O'Brien to Memphis Redbirds. |
| Mar 15 | Angel Gonzalez | Assigned | RHP Angel Gonzalez assigned to St. Louis Cardinals. |
| Mar 15 | Jawilme Ramírez | Assigned | RHP Jawilme Ramirez assigned to St. Louis Cardinals. |
| Mar 15 | Roddery Muñoz | Optioned | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| Mar 14 | Miguel Ugueto | Assigned | LF Miguel Ugueto assigned to St. Louis Cardinals. |
| Mar 14 | Matt Lloyd | Assigned | 3B Matt Lloyd assigned to St. Louis Cardinals. |
| Mar 14 | Tre Richardson III | Assigned | 2B Tre Richardson assigned to St. Louis Cardinals. |
| Mar 14 | Benjamin Arias | Assigned | RHP Benjamin Arias assigned to St. Louis Cardinals. |
| Mar 14 | Nathanael Heredia | Assigned | LHP Nathanael Heredia assigned to St. Louis Cardinals. |
| Mar 13 | Gordon Graceffo | Optioned | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| Mar 13 | Ryan Loutos | Optioned | St. Louis Cardinals optioned RHP Ryan Loutos to Memphis Redbirds. |
| Mar 13 | Bailey Horn | Trade | St. Louis Cardinals traded LHP Bailey Horn to Detroit Tigers. |
| Mar 13 | Bailey Horn | Designated for Assignment | St. Louis Cardinals designated LHP Bailey Horn for assignment. |
| Mar 13 | Phil Maton | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Phil Maton. |
| Mar 12 | Tekoah Roby | Optioned | St. Louis Cardinals optioned RHP Tekoah Roby to Memphis Redbirds. |
| Mar 11 | Deniel Ortiz | Assigned | 3B Deniel Ortiz assigned to St. Louis Cardinals. |
| Mar 11 | Dionys Rodriguez | Assigned | RHP Dionys Rodriguez assigned to St. Louis Cardinals. |
| Mar 11 | Darlin Moquete | Assigned | RF Darlin Moquete assigned to St. Louis Cardinals. |
| Mar 10 | Jacob Buchberger | Assigned | 3B Jacob Buchberger assigned to St. Louis Cardinals. |
| Mar 10 | Mike Antico | Assigned | CF Mike Antico assigned to St. Louis Cardinals. |
| Mar 10 | Tanner Jacobson | Assigned | RHP Tanner Jacobson assigned to St. Louis Cardinals. |
| Mar 10 | Brody Moore | Assigned | 2B Brody Moore assigned to St. Louis Cardinals. |
| Mar 10 | Chris Rotondo | Assigned | RF Chris Rotondo assigned to St. Louis Cardinals. |
| Mar 10 | Michael Watson | Assigned | LHP Michael Watson assigned to St. Louis Cardinals. |
| Mar 10 | Hunter Hayes | Assigned | RHP Hunter Hayes assigned to St. Louis Cardinals. |
| Mar 10 | Yohel Pozo | Assigned | St. Louis Cardinals invited non-roster C Yohel Pozo to spring training. |
| Mar 8 | Sam Brodersen | Assigned | RHP Sam Brodersen assigned to St. Louis Cardinals. |
| Mar 8 | Matt Svanson | Optioned | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| Mar 8 | Sem Robberse | Optioned | St. Louis Cardinals optioned RHP Sem Robberse to Memphis Redbirds. |
| Mar 8 | Yordy Herrera | Assigned | LHP Yordy Herrera assigned to St. Louis Cardinals. |
| Mar 8 | Mason Burns | Assigned | RHP Mason Burns assigned to St. Louis Cardinals. |
| Mar 7 | Hendrick Caña | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Hendrick Cana to a minor league contract. |
| Mar 7 | Tink Hence | Optioned | St. Louis Cardinals optioned RHP Tink Hence to Memphis Redbirds. |
| Mar 7 | Austin Love | Assigned | RHP Austin Love assigned to St. Louis Cardinals. |
| Mar 7 | Hunter Kublick | Assigned | RHP Hunter Kublick assigned to St. Louis Cardinals. |
| Mar 7 | Nelfy Ynfante | Assigned | RHP Nelfy Ynfante assigned to St. Louis Cardinals. |
| Mar 6 | Sem Robberse | Status Change | St. Louis Cardinals reassigned RHP Sem Robberse to the minor leagues. |
| Mar 5 | Zane Mills | Assigned | RHP Zane Mills assigned to St. Louis Cardinals. |
| Mar 4 | Graysen Tarlow | Status Change | C Graysen Tarlow roster status changed by St. Louis Cardinals. |
| Mar 4 | Chase Adkison | Assigned | C Chase Adkison assigned to St. Louis Cardinals. |
| Mar 4 | Johnfrank Salazar | Assigned | 3B Johnfrank Salazar assigned to St. Louis Cardinals. |
| Mar 4 | Andrew Marrero | Assigned | RHP Andrew Marrero assigned to St. Louis Cardinals. |
| Mar 4 | José Suárez | Assigned | RF Jose Suarez assigned to St. Louis Cardinals. |
| Mar 4 | Josh Kross | Assigned | C Josh Kross assigned to St. Louis Cardinals. |
| Mar 4 | Nick Raquet | Assigned | LHP Nick Raquet assigned to St. Louis Cardinals. |
| Mar 4 | Heriberto Caraballo | Assigned | C Heriberto Caraballo assigned to St. Louis Cardinals. |
| Mar 4 | Miguel Villarroel | Assigned | 2B Miguel Villarroel assigned to St. Louis Cardinals. |
| Mar 4 | Graysen Tarlow | Assigned | C Graysen Tarlow assigned to St. Louis Cardinals. |
| Mar 4 | Bailey Horn | Optioned | St. Louis Cardinals optioned LHP Bailey Horn to Memphis Redbirds. |
| Mar 2 | Ian Petrutz | Status Change | OF Ian Petrutz roster status changed by St. Louis Cardinals. |
| Mar 2 | Bailey Horn | Status Change | St. Louis Cardinals reassigned LHP Bailey Horn to the minor leagues. |
| Mar 2 | Bailey Horn | Optioned | St. Louis Cardinals optioned LHP Bailey Horn to Memphis Redbirds. |
| Mar 2 | Ian Petrutz | Assigned | OF Ian Petrutz assigned to St. Louis Cardinals. |
| Mar 2 | Inohan Paniagua | Assigned | RHP Inohan Paniagua assigned to St. Louis Cardinals. |
| Mar 1 | Luis Pino | Assigned | CF Luis Pino assigned to St. Louis Cardinals. |
| Feb 27 | Zach Levenson | Assigned | LF Zach Levenson assigned to St. Louis Cardinals. |
| Feb 27 | Noah Mendlinger | Assigned | RF Noah Mendlinger assigned to St. Louis Cardinals. |
| Feb 26 | Tyler Bradt | Status Change | RHP Tyler Bradt roster status changed by St. Louis Cardinals. |
| Feb 26 | Angel Cuenca | Status Change | RHP Angel Cuenca roster status changed by St. Louis Cardinals. |
| Feb 26 | Joshua Báez | Assigned | RF Joshua Baez assigned to St. Louis Cardinals. |
| Feb 26 | Tyler Bradt | Assigned | RHP Tyler Bradt assigned to St. Louis Cardinals. |
| Feb 26 | Angel Cuenca | Assigned | RHP Angel Cuenca assigned to St. Louis Cardinals. |
| Feb 26 | Luis Gastelum | Assigned | RHP Luis Gastelum assigned to St. Louis Cardinals. |
| Feb 25 | Anyelo Encarnación | Status Change | SS Anyelo Encarnacion roster status changed by St. Louis Cardinals. |
| Feb 25 | Brycen Mautz | Assigned | LHP Brycen Mautz assigned to St. Louis Cardinals. |
| Feb 25 | Anyelo Encarnación | Assigned | SS Anyelo Encarnacion assigned to St. Louis Cardinals. |
| Feb 24 | Chandler Redmond | Status Change | 1B Chandler Redmond roster status changed by St. Louis Cardinals. |
| Feb 24 | Jack Ralston | Status Change | RHP Jack Ralston roster status changed by St. Louis Cardinals. |
| Feb 24 | Leonardo Taveras | Status Change | RHP Leonardo Taveras roster status changed by St. Louis Cardinals. |
| Feb 24 | Jack Ralston | Assigned | RHP Jack Ralston assigned to St. Louis Cardinals. |
| Feb 24 | Leonardo Taveras | Assigned | RHP Leonardo Taveras assigned to St. Louis Cardinals. |
| Feb 24 | Yordalin Peña | Assigned | CF Yordalin Pena assigned to St. Louis Cardinals. |
| Feb 24 | Chandler Redmond | Assigned | 1B Chandler Redmond assigned to St. Louis Cardinals. |
| Feb 24 | Jose Cordoba | Assigned | LF Jose Cordoba assigned to St. Louis Cardinals. |
| Feb 23 | Brayden Jobert | Status Change | OF Brayden Jobert roster status changed by St. Louis Cardinals. |
| Feb 23 | Dakota Harris | Status Change | SS Dakota Harris roster status changed by St. Louis Cardinals. |
| Feb 23 | Osvaldo Berrios | Status Change | RHP Osvaldo Berrios roster status changed by St. Louis Cardinals. |
| Feb 23 | Osvaldo Berrios | Assigned | RHP Osvaldo Berrios assigned to St. Louis Cardinals. |
| Feb 23 | Dakota Harris | Assigned | SS Dakota Harris assigned to St. Louis Cardinals. |
| Feb 23 | Brayden Jobert | Assigned | OF Brayden Jobert assigned to St. Louis Cardinals. |
| Feb 22 | Zack Weiss | Status Change | RHP Zack Weiss roster status changed by St. Louis Cardinals. |
| Feb 22 | Ryan Shreve | Assigned | RHP Ryan Shreve assigned to St. Louis Cardinals. |
| Feb 22 | Zack Weiss | Assigned | RHP Zack Weiss assigned to St. Louis Cardinals. |
| Feb 22 | Rob Kaminsky | Assigned | LHP Rob Kaminsky assigned to St. Louis Cardinals. |
| Feb 18 | Ernie Day | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Ernie Day to a minor league contract. |
| Feb 12 | Rob Kaminsky | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Rob Kaminsky to a minor league contract. |
| Feb 10 | Curtis Taylor | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Curtis Taylor to a minor league contract. |
| Feb 8 | Nick Anderson | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Nick Anderson to a minor league contract and invited him to spring training. |
| Feb 6 | — | Trade | Minnesota Twins traded CF Michael Helman to St. Louis Cardinals for cash. |
| Jan 28 | Victor Santos | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Victor Santos to a minor league contract. |
| Jan 27 | Zack Weiss | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Zack Weiss to a minor league contract. |
| Jan 23 | Yohel Pozo | Signed as Free Agent | St. Louis Cardinals signed free agent C Yohel Pozo to a minor league contract. |
| Jan 18 | Juan García | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Juan Garcia to a minor league contract. |
| Jan 16 | Michael Siani | Number Change | CF Michael Siani changed number to 22. |
| Jan 16 | Bryan Torres | Assigned | St. Louis Cardinals invited non-roster C Bryan Torres to spring training. |
| Jan 16 | Chase Davis | Assigned | St. Louis Cardinals invited non-roster CF Chase Davis to spring training. |
| Jan 16 | Nathan Church | Assigned | St. Louis Cardinals invited non-roster LF Nathan Church to spring training. |
| Jan 16 | R.J. Yeager | Assigned | St. Louis Cardinals invited non-roster 1B R.J. Yeager to spring training. |
| Jan 16 | JJ Wetherholt | Assigned | St. Louis Cardinals invited non-roster SS JJ Wetherholt to spring training. |
| Jan 16 | Jeremy Rivas | Assigned | St. Louis Cardinals invited non-roster 2B Jeremy Rivas to spring training. |
| Jan 16 | César Prieto | Assigned | St. Louis Cardinals invited non-roster 2B César Prieto to spring training. |
| Jan 16 | Wade Stauss | Assigned | St. Louis Cardinals invited non-roster C Wade Stauss to spring training. |
| Jan 16 | Chance Sisco | Assigned | St. Louis Cardinals invited non-roster C Chance Sisco to spring training. |
| Jan 16 | Carlos Linarez | Assigned | St. Louis Cardinals invited non-roster C Carlos Linarez to spring training. |
| Jan 16 | Sammy Hernandez | Assigned | St. Louis Cardinals invited non-roster C Sammy Hernandez to spring training. |
| Jan 16 | Jimmy Crooks | Assigned | St. Louis Cardinals invited non-roster C Jimmy Crooks to spring training. |
| Jan 16 | Gavin Collins | Assigned | St. Louis Cardinals invited non-roster C Gavin Collins to spring training. |
| Jan 16 | Leo Bernal | Assigned | St. Louis Cardinals invited non-roster C Leonardo Bernal to spring training. |
| Jan 16 | Drew Rom | Assigned | St. Louis Cardinals invited non-roster LHP Drew Rom to spring training. |
| Jan 16 | Max Rajcic | Assigned | St. Louis Cardinals invited non-roster RHP Max Rajcic to spring training. |
| Jan 16 | Edwin Núñez | Assigned | St. Louis Cardinals invited non-roster RHP Edwin Nuñez to spring training. |
| Jan 16 | Quinn Mathews | Assigned | St. Louis Cardinals invited non-roster LHP Quinn Mathews to spring training. |
| Jan 16 | Cooper Hjerpe | Assigned | St. Louis Cardinals invited non-roster LHP Cooper Hjerpe to spring training. |
| Jan 16 | Andre Granillo | Assigned | St. Louis Cardinals invited non-roster RHP Andre Granillo to spring training. |
| Jan 16 | Michael Gomez | Assigned | St. Louis Cardinals invited non-roster RHP Michael Gomez to spring training. |
| Jan 16 | Alex Cornwell | Assigned | St. Louis Cardinals invited non-roster LHP Alex Cornwell to spring training. |
| Jan 16 | Ian Bedell | Assigned | St. Louis Cardinals invited non-roster RHP Ian Bedell to spring training. |
| Jan 15 | Michael Cordero | Signed as Free Agent | St. Louis Cardinals signed free agent IF Michael Cordero to a minor league contract. |
| Jan 15 | Nick Raquet | Signed as Free Agent | St. Louis Cardinals signed free agent LHP Nick Raquet to a minor league contract. |
| Jan 15 | Royelny Strop | Signed as Free Agent | St. Louis Cardinals signed free agent OF Royelny Strop to a minor league contract. |
| Jan 15 | Daniel Gómez | Signed as Free Agent | St. Louis Cardinals signed free agent RHP Daniel Gomez to a minor league contract. |
| Jan 15 | Juan Rujano | Signed as Free Agent | St. Louis Cardinals signed free agent SS Juan Rujano to a minor league contract. |
| Jan 15 | Miguel Hernández | Signed as Free Agent | St. Louis Cardinals signed free agent SS Miguel Hernandez to a minor league contract. |
| Jan 15 | Yeferson Portolatin | Signed as Free Agent | St. Louis Cardinals signed free agent SS Yeferson Portolatin to a minor league contract. |
| Jan 15 | Yordy Valdez | Signed as Free Agent | St. Louis Cardinals signed free agent OF Yordy Valdez to a minor league contract. |
| Jan 15 | Jesús Pérez | Signed as Free Agent | St. Louis Cardinals signed free agent SS Jesus Perez to a minor league contract. |
| Jan 15 | Kenly Hunter | Signed as Free Agent | St. Louis Cardinals signed free agent OF Kenly Hunter to a minor league contract. |
| Jan 15 | Sebastian Dos Santos | Signed as Free Agent | St. Louis Cardinals signed free agent SS Sebastian Dos Santos to a minor league contract. |
| Jan 9 | Bailey Horn | Claimed Off Waivers | St. Louis Cardinals claimed LHP Bailey Horn off waivers from Detroit Tigers. |